A UFC Flyweight Championship bout between current champion Deiveson Figueiredo and former UFC Bantamweight Champion Cody Garbrandt was expected to serve as the event headliner. However on October 2, it was announced that Garbrandt pulled out due to a torn bicep and was replaced by Alex Perez, who was already scheduled to face Brandon Moreno at the event. Moreno is now expected to face Brandon Royval.
A UFC Women’s Flyweight Championship bout between current champion Valentina Shevchenko and Jennifer Maia is expected to co-headline the event.
John Allan Arte and Roman Dolidze were originally scheduled to meet at this event in a light heavyweight bout. They were eventually rescheduled for UFC Fight Night 185 in December.
Former UFC Welterweight Champion Robbie Lawler was expected to face Mike Perry at this event. However, Lawler pulled out of the fight in late October citing an undisclosed injury. He was replaced by Tim Means.
A welterweight bout between Orion Cosce and Nicolas Dalby was expected to take place at this event. However on November 12, Cosce pulled out due to undisclosed reasons and was replaced by Daniel Rodriguez.